About jtd

Manuscript Submission

AME Editing Service

Reprint & Permission

Advertising

Contact us

JTD Chinese Edition more

胸外科手术肺漏气与术中出血的诊治:基于Delphi法制定的意大利胸外科学会专家共识

肺持续性漏气和术中出血的诊治是胸外科手术中常见的挑战之一。 More >>

中国香港胸外科现状简介

中国香港的胸外科早在20世纪50年代还是一个新兴的亚专科,主要关注于非解剖性肺切除术和肺结核的开胸治疗。 More >>

中国台湾医疗系统与胸外科发展

中国台湾位于南海以北,距大陆东南沿海约180公里,总面积3.6万平方公里... More >>

Air Pollution more

Age modification of ozone associations with cardiovascular disease risk in adults: a potential role for soluble P-selectin and blood pressure

Drew B. Day, Merlise A. Clyde, Jianbang Xiang, Feng Li, Xiaoxing Cui, Jinhan Mo, Jicheng Gong, Charl... More >>

Assessment of a respiratory face mask for capturing air pollutants
and pathogens including human influenza and rhinoviruses

S. Steve Zhou, Salimatu Lukula, Cory Chiossone, Raymond W. Nims, Donna B. Suchmann, M. Khalid Ijaz More >>

Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens

Xiaoxing Cui, Jicheng Gong, Hailong Han, Linchen He, Yanbo Teng, Teresa Tetley, Rudy Sinharay, Kian ... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng Wa... More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>

Endorsement

Journal of Thoracic Disease is endorsed by: The International COPD Coalition

The International COPD Coalition

The China Asthma Alliance

The China Asthma Alliance

The Brazilian Society of Thoracic Surgery (SBCT)

The Brazilian Society of Thoracic Surgery (SBCT)

The Italian Society of Thoracic Surgery (SICT)

The Italian Society of Thoracic Surgery (SICT)

The Italian VATS Group

The Italian VATS Group

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Hong Kong Society of Endosonography

The Hong Kong Society of Endosonography

Original Article

Perioperative outcomes of robotic versus video-assisted thoracoscopic surgery in non-small cell lung cancer patients after neoadjuvant chemoimmunotherapy
Wangchao Yao, Ziyun Shen, Lele Zhang, Xinsheng Zhu, Yicheng Xiong, Meixin Teng, Yang Qing, Jing Zhang, Peng Zhang
Prognostic factors in lung transplantation after extracorporeal membrane oxygenation bridging therapy: a systematic review and meta-analysis
Yan Zhu, Fei Zeng, Mei-Juan Lan, Jiang-Shu-Yuan Liang, Ling-Yun Cai, Pei-Pei Gu, Lu-Yao Guo
Individualized treatment of type A intramural hematoma—upfront surgery is not always necessary
Simon Chi-Ying Chow, Kevin Lim, Tak-Wai Lum, Jacky Yan-Kit Ho, Song Wan, Takuya Fujikawa, Randolph Hung-Leung Wong
Evaluation of a new surgical procedure for simultaneous resection of synchronous thoracic middle-lower segment esophageal and distal gastric cancers
Xusheng Ding, Bin Li, Hui Shen, Zezhou Wang, Longlong Shao, Jiaqing Xiang
Pazopanib attenuated bleomycin-induced pulmonary fibrosis via suppressing TGF-β1 signaling pathway
Kai Huang, Qianyi Zhang, Hao Ruan, Chunyu Guo, Shuyang Wu, Qinyi Liu, Deqiang Zhang, Shida Long, Wenrui Wang, Zhou Wu, Li Tian, Shuangyan Gao, Huanan Zhao, Xiaoting Gu, Huijun Yin, Cheng Yang
Echocardiographic right ventricular evaluation in cardiac surgery patients undergoing mitral valve reconstruction: a single center prospective observational study
Ali Haddad, Ahmed Mohamed, Sven Arends, Bassam Ishak, Olga Tsarenko, Ilir Balaj, Markus Kamler, Thorsten Brenner, Sharaf-Eldin Shehada
Health-related quality of life after minimal-invasive treatment of aortic valve stenosis in the elderly
Terézia B. Andrási, Celine Schellenberg, Alina Vasiloi, Alannah C. Glück
Suction versus non-suction drainage strategy after uniportal thoracoscopic lung surgery: a prospective cohort study
Yang Qiu, Jian Zhou, Dongsheng Wu, Ailin Luo, Mei Yang, Quan Zheng, Tengyong Wang, Qiang Pu
A validated model to predict spread through air space in lung adenocarcinoma
Yuting Zheng, Xiaoyu Han, Hanting Li, Qinyue Luo, Chengyu Ding, Kailu Zhang, Jun Fan, Wenjuan Zeng, Heshui Shi
Gastrointestinal bleeding risk factors in type A aortic dissection post-aortic arch replacement
Junhai Hao, Jiaxin Li, Hanxiao Zhang, Jia Chen, Miaoxian Fang, Meifen Wu, Bowen Gu, Yingkai Xiao, Liming Lei
Yiqigubiao pill treatment regulates Sirtuin 5 expression and mitochondrial function in chronic obstructive pulmonary disease
Ting Meng, Feng-Sen Li, Dan Xu, Jing Jing, Zheng Li, Miyesier Maimaitiaili, Yong-Jiang Bao
Clinical outcomes of radiofrequency catheter ablation guided by intracardiac echocardiography for Chinese atrial fibrillation patients: a single-center, retrospective study
Dongchen Zhou, Jian Yang, Biqi Zhang, Jie Han, Chenyu Zuo, Xingwei Lu, Jianwei Xuan, Xiaogang Guo
Compatible with fibrotic hypersensitivity pneumonitis on high-resolution computed tomography: from the ATS/JRS/ALAT 2020 hypersensitivity pneumonitis guidelines
Shota Kaburaki, Ryo Okuda, Tamiko Takemura, Eri Hagiwara, Masahiro Seike, Akihiko Gemma, Takashi Ogura
Subnormothermic ex vivo lung perfusion possibly protects against ischemia-reperfusion injury via the mTORC-HIF-1α pathway
Jee Won Suh, Soo Jin Park, Young Wha Koh, Daun Seo, Seokjin Haam
Safety and efficacy of delayed completion lobectomy following wedge resection vs. segmentectomy—a retrospective cohort study
Yimu Wu, Kaiqi Jin, Linlin Qin, Zhaoxun Li, Xiaoxiong Xu, Jie Dai, Xiaogang Liu, Xinnan Xu, Xiao Zhou, Gening Jiang
Early and mid-term outcomes of tricuspid valve surgery in patients with functional tricuspid regurgitation induced by atrial fibrillation
Eun Chae Kim, Nazla Amanda Soehartono, Sue Hyun Kim, Yeiwon Lee, Suk Ho Sohn, Ho Young Hwang, Kyung Hwan Kim, Jae Woong Choi
Relationship of various COVID-19 antibody titer with individual characteristics and prediction of future epidemic trend in Xiamen City, China
Liansheng Xu, Buasiyamu Abudunaibi, Zhiqi Zeng, Yunkang Zhao, Yao Wang, Xiaohao Guo, Yidun Zhang, Tao Li, Wenkui Lu, Weiliang Tian, Zhinan Guo, Chenghao Su, Tianmu Chen
Screening and identification of hub genes for ischemic cardiomyopathy and construction and validation of a clinical prognosis model using bioinformatics analysis
Jing Wang, Liying Tang, Yuzhi Bai, Xia Zhao, Tian Tian, Christos G. Mihos, Eva Maria Javier Delmo, Pei Li
Prognostic impact of spread through air spaces in patients with ≤2 cm stage IA lung adenocarcinoma
Xiao Chen, Hangcheng Zhou, Mingsheng Wu, Meiqing Xu, Tian Li, Jun Wang, Xiaohui Sun, Yasuhiro Tsutani, Mingran Xie
Transcriptome analysis revealed the new mechanism of the intra-myocardial injectable alginate-hydrogel in the treatment of ventricular function degradation
Huiyong Wang, Ting Zhou, Wentao Ma, Ji Zheng, Zhiyong Cao, Caiyun He, Pedro A. Lemos, Jianfang Luo
CXCR7 promotes pulmonary vascular remodeling via targeting p38/MMP2 pathway in pulmonary arterial hypertension
Jingjing Xu, Shuai Miao, Tianjun Wu, Chunxiao Hu, Dongxiao Huang, Xin Zhang
A preliminary study of modified inflatable mediastinoscopic and single-incision plus one-port laparoscopic esophagectomy
Hua Tang, Zhihao Song, Rongqiang Wei, Kai Yan, Zihao Chen, Kenan Huang, Ning Xin, Noriyuki Hirahara, Inderpal S. Sarkaria, Xinyue Li, Bin Wu, Zhifei Xu
Developing and validating machine learning-based prediction models for frailty occurrence in those with chronic obstructive pulmonary disease
Yong Chen, Yonglin Yu, Dongmei Yang, Wenbo Zhang, Vasileios Kouritas, Xiaoju Chen
Accurate etiological diagnosis of Mycoplasma hominis mediastinitis in immunocompetent patients using metagenomic next-generation sequencing: a case series and literature review
Sishi Cai, Jue Pan, Suzhen Wang, Rong Bao, Chunmei Zhou, Xiaodong Gao, Haruhiko Shiiya, Bijie Hu
ALAS2 overexpression alleviates oxidative stress-induced ferroptosis in aortic aneurysms via GATA1 activation
Yunjun He, Xiaohui Wang, Donglin Li, Qianqian Zhu, Yilang Xiang, Yangyan He, Hongkun Zhang
The predictive and prognostic value of risk factors in patients receiving hybrid coronary revascularization with postoperative pulmonary complications
Shanshan Mu, Yingqi Chen, Jiawan Wang, Jingjing Guo, Ruitong Niu, Yang Zhang, Pixiong Su, Jason M. Ali, Jie Gao, Anshi Wu
Etiological diagnostic performance of probe capture-based targeted next-generation sequencing in bloodstream infection
Sishi Cai, Jianying Yuan, Yingzhen Li, Fengming Guo, Zengshun Lin, Hongyi Li, Qing Miao, Tingting Fang, Yuan Wu, Xiaodong Gao, Pei Li, Jun Liu, Chaohui Hu, Bijie Hu
An esophagectomy surgical Apgar score-based nomogram—a risk-based postoperative triage system: a phase II randomised trial
Xiaohan Chen, Yong Xi, Chengbin Lin, Hongyan Yu, Jae Y. Kim, Jon O. Wee, Xianneng He, Jiajun Gao, Weiyu Shen
Automatic 3D coronary artery segmentation based on local region active contour model
Xiaohong Chen, Jufeng Jiang, Xiaofeng Zhang
Revealing the oncogenic role of elevated GNL3L expression in esophageal squamous cell carcinoma: insights into the STAT3 pathway
Shaobin Yu, Peipei Zhang, Shaojun Xu, Zhang Xiang, Ankit Madan, Guy D. Eslick, Farshid Dayyani, Shuchen Chen
The quality of life of patients with chronic obstructive pulmonary disease: a bibliometric analysis
Xiaxia Wu, Zhongyang Liu, Chenpan Xu, Till Plönes, Hong Wang

Review Article

Enhanced recovery after chest wall resection and reconstruction: a clinical practice review
Céline Forster, Valentin Jacques, Etienne Abdelnour-Berchtold, Thorsten Krueger, Jean Yannis Perentes, Matthieu Zellweger, Michel Gonzalez
Patient selection, surgery and perioperative management in lung transplantation in Japan
Chihiro Konoeda, Masaaki Sato
Blood flow assessment technology in aortic surgery: a narrative review
Yu Hohri, Megan M. Chung, Viswajit Kandula, Ilya Kim, Jay Leb, Hideyuki Hayashi, Adham Elmously, Thomas FX O’Donnell, Virendra Patel, Vijay Vedula, Hiroo Takayama
Extracorporeal membrane oxygenation for general thoracic surgery: case series and narrative review
Megan E. Campany, Britton B. Donato, Pedro Reck dos Santos, Cory M. Alwardt, Kristin Sell-Dottin, Stephanie Blakeman, Penny Hung, Ayan Sen, Patrick DeValeria, Lara Schaheen, Jonathan D’Cunha
Machine learning in cardiac surgery: a narrative review
Travis J. Miles, Ravi K. Ghanta
Automatic detection of obstructive sleep apnea based on speech or snoring sounds: a narrative review
Shuang Cao, Ivana Rosenzweig, Federico Bilotta, Hong Jiang, Ming Xia

Editorial Commentary

The ideal regional block after video-assisted thoracoscopic surgery: do we have it?
Sarah Lumsden, Emily Lai, Juan P. Cata
Is paravertebral block the new standard of care for postoperative analgesia after thoracoscopic surgery?
Alberto Aiolfi, Davide Bona, Galyna Shabat, Marco Resta, Luigi Bonavina
Not all that glitters is gold
Marco Anile, Francesco Ferrante, Beatrice Zacchini, Angelina Pernazza, Massimiliano Bassi, Jacopo Vannucci, Federico Venuta
Pure ground-glass opacity of the lung: making the case for a lasting cure
Mohammad Abdallat, Danny Jonigk, Hassan A. Khalil
The impact of neoadjuvant therapy on postoperative outcomes following sleeve lobectomy for locally advanced non-small cell lung cancer: a call for future investigation
Rajika Jindani, Brendon Stiles
Neoadjuvant therapy and sleeve lobectomy for locally advanced non-small cell lung cancer: morbidity and survival balancing
Alessio Campisi, Giorgio Cannone, Vincenzo Verzeletti, Andrea Dell’Amore
Advancing coronary artery bypass grafting: the fasudil-nitroglycerin cocktail as a potential antispastic solution
Michael Dashwood, Domingos Souza, Gökce Topal
Global implementation of individualized lung cancer care requires wide adoption of molecular tumor profiling
Nathaniel Deboever, Mara B. Antonoff

Images in Clinical Medicine

COVID-19 infection in a lung transplant recipient
Yuan Zeng, Guilin Peng, Chao Yang, Mengyang Liu, Jianxing He, Xin Xu

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution
Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen
Delays in the diagnosis of lung cancer
Peter M Ellis, Rachel Vandermeer
The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions
Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi
Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung
Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano
Theoretical models of carcinogenic particle deposition and clearance in children’s lungs
Robert Sturm
A novel paradigm in the treatment of oligometastatic non-small cell lung cancer
Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner
Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes
Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data
Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators
High prevalence of gene abnormalities in young patients with lung cancer
Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients
Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown
Thoracic malignant solitary fibrous tumors: A population-based study of survival
Michael T Milano, Deepinder P Singh, Hong Zhang
Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)
Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi
High-resolution CT findings of patients with pulmonary nocardiosis
Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto
Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer
Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Review Article

Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Nontuberculous mycobacterial pulmonary infections
Margaret M. Johnson, John A. Odell
Treatment of advanced non small cell lung cancer
Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli
Chemotherapy advances in small-cell lung cancer
Bryan A. Chan, Jermaine I. G. Coward
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Peter Savas, Brett Hughes, Benjamin Solomon
Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies
Suresh Senan, David A. Palma, Frank J. Lagerwaard
The anticipation and management of air leaks and residual spaces post lung resection
Michael Rolf Mueller, Beatrice A. Marzluf
Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy
Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman
Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era
Zarnie Lwin, Jonathan W. Riess, David Gandara
MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets
Glen Reid
Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?
Giles Dixon, Duneesha de Fonseka, Nick Maskell
Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature
Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black
Active-specific immunotherapy for non-small cell lung cancer
Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger
Advanced imaging in COPD: insights into pulmonary pathophysiology
Stephen Milne, Gregory G. King
Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)
Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua
Diagnosis and early detection of COPD using spirometry
David P. Johns, Julia A.E. Walters, E. Haydn Walters
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Pediatric lung transplantation: indications and outcomes
Stephen Kirkby, Don Hayes Jr
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD
Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro
Lung donor selection criteria
John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel
Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer
Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu
Lung cancer screening: identifying the high risk cohort
Michael W. Marcus, Olaide Y. Raji, John K. Field
Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions
Marc Fortin, Alain Tremblay
New techniques for assessing response after hypofractionated radiotherapy for lung cancer
Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma
Supportive and palliative care for lung cancer patients
Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways
Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr
Severe amiodarone induced pulmonary toxicity
Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer
Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase
R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells
Klaus Pantel, Catherine Alix-Panabières

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success
Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee
Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique
Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Review Article

Atypical antibody responses to influenza
Dalton Hermans, Richard J. Webby, Sook-San Wong
What can individuals do to reduce personal health risks from air pollution?
Robert Laumbach, Qingyu Meng, Howard Kipen
The role of rotors in atrial fibrillation
David E. Krummen, Vijay Swarup, Sanjiv M. Narayan
Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Esophageal cancer: staging system and guidelines for staging and treatment
Mark F. Berry
Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts
Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli
Premature menopause in young breast cancer: effects on quality of life and treatment interventions
Shoshana M. Rosenberg, Ann H. Partridge
Strategies for the acquisition of transcriptional and epigenetic information in single cells
Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu
The role of transforming growth factor (TGF)-β in the infarcted myocardium
Nikolaos G. Frangogiannis
Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery
Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft
Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma
Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Editorial

Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Sleep and critical illness: bridging the two pillars at the ATS 2016
Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens
Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient
John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella
Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk
Kavisha Singh, Anand Rohatgi
Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data
Susan Kuldanek, Christopher C. Silliman
Optogenetic tools for cell biological applications
Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”
Chia-Ju Liu, Wei Lu
The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?
Bo Xu, Reena Mehra
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Allosterically targeting EGFR drug-resistance gatekeeper mutations
Nicholas Spellmon, Chunying Li, Zhe Yang
Imaging homeostatic sleep pressure and circadian rhythm in the human brain
Zhuo Fang, Hengyi Rao
Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer
Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”
Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan
The role of a decision analysis in treatment of T2N0 esophageal cancer
Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy
Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal
A novel strategy for cardiopulmonary support during lung transplantation
Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals
Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept
Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.